What are the risk factors for thrombophilia? – Genofit Australia

Injury and surgery (and immobility during recovery)
Infections
Inflammatory disease
Diabetes
Cancer and cancer treatments
Sedentary lifestyle
Obesity
Smoking
Hormonal changes (e.g. contraceptive pills, hormone replacement therapies, pregnancy)
High homocysteine levels in the blood (Vitamin B deficiency, reduced kidney, liver or thyroid function, increased blood pressure, certain drugs, and excess coffee can lead to elevated homocysteine levels)
Genetic risk factors:
- F5 (Factor V) Leiden mutation (1691G>A)
- F2 (Prothrombin) 20210G>A mutation
- MTHFR - 677C>T and 1298A>C mutations result in increased homocysteine levels